GENERAL CATALOGUE
PLK1-IN-9
HY-W276819 · 50 mg
MedChemExpress · Cat: HY-W276819
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medchemexpress.com/plk1-in-9.htmlCatalog No: HY-W276819
CAS No: 893772-67-3
Category: Cell Cycle DNA Damage
Pack Size: 50 mg
Brand: MedChemExpress
Description
PLK1-IN-9 Compound M2 is an inhibitor for polo-like kinase 1 PLK1 , that inhibits PLK proteins modified with peptides 1010pT, cdc25c and PBIP, with IC50s of 1.6, 0.8 and 1.4 ?M, respectively. PLK1-IN-9 inhibits proliferations of cancer cells HeLa, HL60, SNU387/499, HepG2, exhibits cytotoxicity and induces apoptosis. PLK1-IN-9 inhibits tumor growth in HepG2 xenograft mouse model.
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