GENERAL CATALOGUE
PLN-1474
HY-47888 · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-47888
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Manufacturer product page
medchemexpress.com/pln-1474.htmlCatalog No: HY-47888
CAS No: 2408065-32-5
Category: Cytoskeleton
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress
Description
PLN-1474 compound 1 is an orally active and selective ???1 integrin inhibitor with an IC50 value of <50 nM. PLN-1474 reduces levels of pSMAD3/SMAD3 in liver, hepatic collagen gene expression and hepatic OHP concentration in liver fibrosis mouse model. PLN-1474 can be used for the research of preventing, delaying or researching a fibrotic or cirrhotic disease or disorder.
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