GENERAL CATALOGUE
PMX-53
HY-106178 · 5 mg
MedChemExpress · Cat: HY-106178
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Catalog No: HY-106178
CAS No: 219639-75-5
Category: Immunology Inflammation
Pack Size: 5 mg
Brand: MedChemExpress
Description
PMX-53 3D53 is a synthetic peptidic and a potent and orally active complement C5a receptor CD88 antagonist with an IC50 of 20 nM. PMX-53 is also a low-affinity MrgX2 agonist that stimulates MrgX2-mediated mast cell degranulation. PMX-53 specifically binds to C5aR1 and does not bind to the second C5aR C5L2 and C3aR. PMX-53 has anti-inflammatory, anticancer and antiatherosclerotic effects.
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