GENERAL CATALOGUE
PNU-159682
HY-16700 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-16700
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Catalog No: HY-16700
CAS No: 202350-68-3
Category: Antibody-drug Conjugate ADC Related
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
PNU-159682, a metabolite of the anthracycline Nemorubicin, is a highly potent DNA topoisomerase II inhibitor with excellent cytotoxicity. PNU-159682 acts as a more potent and tolerated ADC cytotoxin than Doxorubicin for ADC synthesis. PNU-159682 can be used in EDV-nanocell technology to overcome agent resistance.
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