GENERAL CATALOGUE
PNU-183792
HY-148852 · 5 mg
MedChemExpress · Cat: HY-148852
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medchemexpress.com/pnu-183792.htmlCatalog No: HY-148852
CAS No: 282536-25-8
Category: Anti-infection
Pack Size: 5 mg
Brand: MedChemExpress
Description
PNU-183792, a 4-oxo-dihydroquinoline, is an orally active HSV polymerases inhibitor. PNU-183792 shows a broad-spectrum antiviral activity, with IC50 values of 0.69 ?M, 0.37 ?M and 0.58 ?M for human cytomegalovirus HCM , varicella zoster virus and HSV polymerases, respectively. PNU-183792 is inactive against human ?, ? and ? polymerases. PNU-183792 also inhibits simian varicella virus SVV , murine cytomegalovirus MCMV and rat cytomegalovirus RCMV .