GENERAL CATALOGUE
Pol?-IN-4
HY-161916 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-161916
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medchemexpress.com/pol%CE%B8-in-4.htmlCatalog No: HY-161916
CAS No: 3043810-73-4
Category: Cell Cycle DNA Damage
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
Pol?-IN-4 is an orally active prodrug of a DNA polymerase ? Pol? inhibitor with Kms of 3.7, 3.7 and 5.2 ?M in human, mouse and rat recombinant alkaline phosphatases. Pol?-IN-4 that inhibits Pol? activity by targeting its ATP-dependent helicase domain. Pol?-IN-4 demonstrates significant anti-tumor activity in multiple animal experiments. Pol?-IN-4 can be used for the studies of breast cancer and ovarian cancer.
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