GENERAL CATALOGUE
Pol?/PARP-IN-1
HY-161302 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-161302
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medchemexpress.com/pol%CE%B8-parp-in-1.html
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Catalog No: HY-161302
Category: Apoptosis
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
Pol?/PARP-IN-1 compound 25d is a potent dual DNA polymerase theta Pol? and PARP inhibitor with IC50 values of 45.6, 5.4 nM, respectively. Pol?/PARP-IN-1 shows antiproliferative activity. Pol?/PARP-IN-1 induces apoptosis and cell cycle arrest at G2/M phase, causes DNA damage. Pol?/PARP-IN-1 shows anti-tumor activity.
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