GENERAL CATALOGUE
Poloxin-2
HY-129265 · 1 mg
MedChemExpress · Cat: HY-129265
₹550 – ₹850 approx.This price excludes freight and taxes. Please RFQ to get the final price.
Reach 3+ verified distributors
Manufacturer product page
medchemexpress.com/poloxin-2.html
Sponsored
Catalog No: HY-129265
CAS No: 321695-37-8
Category: Cell Cycle DNA Damage
Pack Size: 1 mg
Brand: MedChemExpress
Description
Poloxin-2 is a small molecule Plk1 PBD inhibitor that can effectively induce cell mitotic arrest with an EC50 of approximately 15 ?M in HeLa cells. Poloxin-2HT was developed by conjugating a hydrophobic tag HT to Poloxin-2, a new application of inhibitors targeting protein-protein interactions. Poloxin-2HT significantly enhanced the effects on cell viability and apoptosis by selectively degrading Plk1 protein, and its effect was stronger than that of untagged Poloxin-2. These data validate hydrophobic tags as a new strategy for targeting and disrupting disease-associated proteins.
More from MedChemExpress
TP-061
HY-103041
Cell Cycle DNA Damage
Guttiferone G
HY-N9892
Cell Cycle DNA Damage
C
Cdk14 Mouse Pre-designed siRNA Set A
HY-RS02363
Cell Cycle DNA Damage
HSP70/SIRT2-IN-2
HY-149638
Cell Cycle DNA Damage
Tucidinostat (Standard)
HY-109015R
Cell Cycle DNA Damage
C
CDK2 Human Pre-designed siRNA Set A
HY-RS02374
Cell Cycle DNA Damage
Palmitic acid-d2-1
HY-N0830S11
Cell Cycle DNA Damage
Cdc7-IN-1
HY-101523
Cell Cycle DNA Damage