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POLQ
GENERAL CATALOGUE

POLQ

RP-D00004 · 20 ug

GenScript · Cat: RP-D00004

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Catalog No: RP-D00004
Category: protein
Pack Size: 20 ug
Brand: GenScript

Description

Low-fidelity DNA polymerase with a helicase activity that promotes microhomology-mediated end-joining MMEJ , an alternative non-homologous end-joining NHEJ machinery required to repair double-strand breaks in DNA during mitosis. POLQ is often overexpressed in various cancers, especially those with HR deficiencies, such as BRCA1/2-mutated cancers.

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