GENERAL CATALOGUE
Ponalrestat
HY-106697 · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-106697
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Catalog No: HY-106697
CAS No: 72702-95-5
Category: Metabolic Enzyme Protease
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress
Description
Ponalrestat ICI 128436 is an orally active, selective and noncompetitive aldose reductase AKR1B1; ALR inhibitor. Ponalrestat selectively inhibits ALR2 Ki=7.7 nM over ALR1 Ki=60 ?M . Ponalrestat inhibits the conversion of glucose to sorbitol.
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