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PPAR? agonist 11
GENERAL CATALOGUE

PPAR? agonist 11

HY-162963 · 50 mg

MedChemExpress · Cat: HY-162963

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Catalog No: HY-162963
CAS No: 2982696-04-6
Category: Cell Cycle DNA Damage
Pack Size: 50 mg
Brand: MedChemExpress

Description

PPAR? agonist 11 Compound 11 is a selective agonist for PPAR? with an EC50 of 20 nM. PPAR? agonist 11 reduces the levels of nitrite oxide NO , proinflammatory cytokines TNF? and IL-6 in LPS HY-D1056 -stimulated RAW264.7 cell, and exhibits anti-inflammatory efficacy via NF-?B pathway. PPAR? agonist 11 exhibits good stability in human liver microsomes and plasma. PPAR? agonist 11 ameliorates Carrageenan HY-125474 -induced foot edema.

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