

HY-162963 · 50 mg
MedChemExpress · Cat: HY-162963
Reach 3+ verified distributors
Manufacturer product page
medchemexpress.com/ppar%CE%B4-agonist-11.html
Description
PPAR? agonist 11 Compound 11 is a selective agonist for PPAR? with an EC50 of 20 nM. PPAR? agonist 11 reduces the levels of nitrite oxide NO , proinflammatory cytokines TNF? and IL-6 in LPS HY-D1056 -stimulated RAW264.7 cell, and exhibits anti-inflammatory efficacy via NF-?B pathway. PPAR? agonist 11 exhibits good stability in human liver microsomes and plasma. PPAR? agonist 11 ameliorates Carrageenan HY-125474 -induced foot edema.





