GENERAL CATALOGUE
Prexasertib mesylate
HY-18174C · 50 mg
MedChemExpress · Cat: HY-18174C
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Manufacturer product page
medchemexpress.com/prexasertib-mesylate.htmlCatalog No: HY-18174C
CAS No: 1234015-55-4
Category: Apoptosis
Pack Size: 50 mg
Brand: MedChemExpress
Description
Prexasertib mesylate LY2606368 mesylate is a selective, ATP-competitive second-generation checkpoint kinase 1 CHK1 inhibitor with a Ki of 0.9 nM and an IC50 of 1 nM. Prexasertib mesylate inhibits CHK2 IC50=8 nM and RSK1 IC50=9 nM . Prexasertib mesylate causes double-stranded DNA breakage and replication catastrophe resulting in apoptosis. Prexasertib mesylate shows potent anti-tumor activity.
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