GENERAL CATALOGUE
PRMT5-IN-19
HY-149005 · 50 mg
MedChemExpress · Cat: HY-149005
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Manufacturer product page
medchemexpress.com/prmt5-in-19.htmlCatalog No: HY-149005
CAS No: 2783961-86-2
Category: Epigenetics
Pack Size: 50 mg
Brand: MedChemExpress
Description
PRMT5-IN-19 Compound 41 is an selective orally active non-nucleoside PRMT5 inhibitor with IC50 values of 23.9 nM radioactive biochemical assay and 47 nM AlphaLISA assay . PRMT5-IN-19 can occupy the SAM-binding pocket in PRMT5 and block methyltransferase activity, which displays good selectivity over other PRMTs and PKMTs. PRMT5-IN-19 inhibits cell proliferation by inducing cell apoptosis, and can be used for cancer-related research.
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