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PRMT5-IN-31
GENERAL CATALOGUE

PRMT5-IN-31

HY-155050 · 10 mM * 1 mL in DMSO

MedChemExpress · Cat: HY-155050

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medchemexpress.com/prmt5-in-31.html
Catalog No: HY-155050
Category: Apoptosis
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress

Description

PRMT5-IN-31 Compound 3m is a selective PRMT5 inhibitor IC50: 0.31 ?M . PRMT5-IN-31 up-regulates hnRNP E1 protein level. PRMT5-IN-31 occupies the substrate site of PRMT5 and forms essential interactions with amino acid residues. PRMT5-IN-31 has antiproliferative effects against A549 cells by inducing apoptosis and inhibiting cell migration. PRMT5-IN-31 has high metabolic stability on human liver microsomes T1/2: 132.4 min .

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