GENERAL CATALOGUE
PRMT5-IN-50
HY-172732 · 50 mg
MedChemExpress · Cat: HY-172732
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Manufacturer product page
medchemexpress.com/prmt5-in-50.htmlCatalog No: HY-172732
CAS No: 3002409-47-1
Category: Epigenetics
Pack Size: 50 mg
Brand: MedChemExpress
Description
PRMT5-IN-50 is an orally active and selective inhibitor of PRMT5. PRMT5-IN-50 has good metabolic stability and low clearance rate in human liver microsomes. PRMT5-IN-50 inhibits SDMA/HCT116-MTAPdel and SDMA/HCT116-MTAPwt with IC50s value of 1.0, 536 nM for arginine symmetric methylation, 19, 1620 nM for anti-proliferation, respectively. PRMT5-IN-50 inhibits tumor growth in mice.
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