GENERAL CATALOGUE
PRMT5-MTA-IN-1
HY-163799 · 50 mg
MedChemExpress · Cat: HY-163799
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Manufacturer product page
medchemexpress.com/prmt5-mta-in-1.htmlCatalog No: HY-163799
CAS No: 3048425-88-0
Category: Epigenetics
Pack Size: 50 mg
Brand: MedChemExpress
Description
PRMT5-MTA-IN-1 Compound A9a is an inhibitor for protein arginine methyltransferase PRMT5-MTA. PRMT5-MTA-IN-1 inhibits the proliferation of colorectal cancer cell HCT116 wildtype and MTAP del mutant, with an IC50 of 16 nM and 2.47 ?M. PRMT5-MTA-IN-1 exhibits good liver microsomal stability and film permeability. PRMT5-MTA-IN-1 exhibits good pharmacokinetic characteristics in CD-1 mice.
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