GENERAL CATALOGUE
PRMT5-MTA-IN-3-d3
HY-172733S · 50 mg
MedChemExpress · Cat: HY-172733S
Reach 3+ verified distributors
Manufacturer product page
medchemexpress.com/prmt5-mta-in-3-d3.htmlCatalog No: HY-172733S
CAS No: 3052146-54-7
Category: Epigenetics
Pack Size: 50 mg
Brand: MedChemExpress
Description
PRMT5-MTA-IN-3-d3 compound P22 is the deuterium labeled PRMT5-MTA-IN-3 HY-172733 . PRMT5-MTA-IN-3-d3 is an orally active PRMT5-MTA inhibitor. PRMT5-MTA-IN-3-d3 has antiproliferative effects on HTC116-MTAP del and wild type colorectal cancer HCT-116 cell lines, with IC50 values of 6 nM and 961 nM, respectively. PRMT5-MTA-IN-3-d3 has anticancer effects, especially for MTAP-deficient tumors, such as non-small cell lung cancer NSCLC , pancreatic cancer.