pro Caspase 7 (10O2) Rabbit Monoclonal Antibody

Description

EnkiLife offers the pro Caspase 7 (10O2) Rabbit Monoclonal Antibody. This antibody reacts with Human species and is suitable for WB,IHC,ICC/IF application. Alternative Names of Immunogen: apoptosis-related cysteine peptidase; Apoptotic protease Mch-3; CASP-7; Caspase-7 subunit p11; CMH-1; ICE-LAP3; ICE-like apoptotic protease 3;. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1000-1:2000,IHC 1:100-1:200,ICC/IF 1:50-1:200 Background: Belongs to the peptidase C14A family. Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp--Gly-217' bond. Overexpression promotes programmed cell death. Involved in the activation cascade of caspases responsible for apoptosis execution (PubMed:8521391, PubMed:8576161, PubMed:8567622, PubMed:9070923, PubMed:11701129). Cleaves and activates sterol regulatory element binding proteins (SREBPs) (PubMed:8521391, PubMed:8576161, PubMed:8567622, PubMed:9070923). Proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Overexpression promotes programmed cell death (PubMed:8521391, PubMed:8576161, PubMed:8567622, PubMed:9070923). Cleaves phospholipid scramblase proteins XKR4, XKR8 and XKR9 (By similarity).