GENERAL CATALOGUE
Propafenone
HY-B0432 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-B0432
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Catalog No: HY-B0432
CAS No: 54063-53-5
Category: GPCR G Protein
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
Propafenone SA-79 , a sodium-channel blocker, acts an antiarrhythmic agent. Propafenone also has high affinity for the ? receptor IC50=32 nM . Propafenone blocks the transient outward current Ito and the sustained delayed rectifier K current Isus with IC50 values of 4.9??m and 8.6??m, respectively. Propafenone suppresses esophageal cancer proliferation through inducing mitochondrial dysfunction and induce apoptosis.
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