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PROTAC ATR degrader-2
GENERAL CATALOGUE

PROTAC ATR degrader-2

HY-161615 · 5 mg

MedChemExpress · Cat: HY-161615

₹450 – ₹650 approx.This price excludes freight and taxes. Please RFQ to get the final price.

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Catalog No: HY-161615
CAS No: 3010273-12-5
Category: Apoptosis
Pack Size: 5 mg
Brand: MedChemExpress

Description

PROTAC ATR degrader-2 Compound 8i is a PROTAC degrader for ATR, through of . PROTAC ATR degrader-2 degrades ATR in acute myeloid leukemia AML cells MV-4-11 and MOLM-13, with DC50 of 22.9 and 34.5 nM. APROTAC ATR degrader-2 induces apoptosis, inhibits proliferations of AML cells. PROTAC ATR degrader-2 exhibits good pharmacokinetics charachers and antitumor efficacy against AML in mouse model. Pink: ATR ligand HY-161616 ; Blue:E3 ligase ligand Lenalidomide HY-A0003 ; Black: linker

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