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PROTAC BET Degrader-12
GENERAL CATALOGUE

PROTAC BET Degrader-12

HY-158764 · 5 mg

MedChemExpress · Cat: HY-158764

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Catalog No: HY-158764
Category: Epigenetics
Pack Size: 5 mg
Brand: MedChemExpress

Description

PROTAC BET Degrader-12 Compound 8b is a PROTAC degrader for bromodomain and extra-terminal domain BET -containing proteins, which degrades the BRD3 and BRD4 in a DCAF11-dependent manner. PROTAC BET Degrader-12 inhibits cell viability of KBM7 with a DC50 of 305.2 nM. Pink: ligand for target protein + -JQ-1 HY-13030 ; Black: linker HY-159077 ; Blue: ligand for E3 ligase HY-159076

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