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PROTAC BET Degrader-13
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PROTAC BET Degrader-13

HY-175354 · 50 mg

MedChemExpress · Cat: HY-175354

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Catalog No: HY-175354
Category: Epigenetics
Pack Size: 50 mg
Brand: MedChemExpress

Description

PROTAC BET Degrader-13 Compound 34 is a TRIM21-based PROTAC TRIMTAC degrader targeting BET. PROTAC BET Degrader-13 significantly degrades PML-eGFP-BRD4 fusion protein with a near-complete loss of EGFP+ nuclear puncta with an EC50 of 1.4 ?M. Pink: BET ligand HY-13030 ; Blue: E3 ligase ligand HY-W1125585 ; Black: linker

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