GENERAL CATALOGUE
PROTAC BRD4 Degrader-12
HY-138635 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-138635
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Catalog No: HY-138635
CAS No: 2417370-90-0
Category: Epigenetics
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
PROTAC BRD4 Degrader-12 compound 9c is a PROTAC connected by ligands for von Hippel-Lindau and BRD4. PROTAC BRD4 Degrader-12 can be conjugated with STEAP1 and CLL1 antibodies to degrade the BRD4 protein in PC3 prostate cancer cells, with a DC50 of 0.39 nM and 0.24 nM, respectively.