GENERAL CATALOGUE
PROTAC BRD4 Degrader-32
HY-176449 · 50 mg
MedChemExpress · Cat: HY-176449
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medchemexpress.com/protac-brd4-degrader-32.htmlCatalog No: HY-176449
Category: Epigenetics
Pack Size: 50 mg
Brand: MedChemExpress
Description
PROTAC BRD4 Degrader-32 Compound 22 is a BRD4 PROTAC degrader DC50: 0.20 nM . PROTAC BRD4 Degrader-32 connects the BRD4-binding domain and CRBN-binding domain through a unique carbon-carbon linked linker to form a ternary complex, inducing ubiquitination of BRD4 for proteasomal degradation. PROTAC BRD4 Degrader-32 is promising for research of BRD4-related cancers such as hematological malignancies . Pink: GSK1324726A HY-13960 ; Black: linker HY-176450 ; Blue: Lenalidomide-5-Br HY-W072954 .