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PROTAC BRD4 Degrader-33
GENERAL CATALOGUE

PROTAC BRD4 Degrader-33

HY-174811 · 50 mg

MedChemExpress · Cat: HY-174811

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Catalog No: HY-174811
Category: Epigenetics
Pack Size: 50 mg
Brand: MedChemExpress

Description

PROTAC BRD4 Degrader-33 is an enzyme activated clickable BRD4 PROTAC degrader with favorable tumor microenvironment-response. PROTAC BRD4 Degrader-33 has superior tumor tissue penetration capabilities and efficiently inhibits PD-L1 protein expression. PROTAC BRD4 Degrader-33 shows potent anti-tumoral immunomodulation activity in 4T1 tumor-bearing mice model. Pink: BRD4 ligand HY-174812 ; Blue: CRBN ligase ligand HY-10984 ; Black: linker

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