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PROTAC BRD4 Degrader-38
GENERAL CATALOGUE

PROTAC BRD4 Degrader-38

HY-175240 · 50 mg

MedChemExpress · Cat: HY-175240

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Catalog No: HY-175240
Category: Epigenetics
Pack Size: 50 mg
Brand: MedChemExpress

Description

PROTAC BRD4 Degrader-38 is a BRD4 PROTAC degrader with DC50s of 86 and 106 nM for the short and long isoforms of BRD4, respectively. PROTAC BRD4 Degrader-38 significantly induces the degradation of BRD4 by covalently engaging C232 of E3 ligase TRIM28.Pink: BRD4 ligand HY-78695 ; Blue: E3 ligase ligand HY-203082 ; Black: linker HY-40172

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