

HY-130709 · 5 mg
MedChemExpress · Cat: HY-130709
Reach 3+ verified distributors
Manufacturer product page
medchemexpress.com/protac-cdk2-9-degrader-1.htmlDescription
PROTAC CDK2/9 Degrader-1 Compound F3 is a potent dual degrader for CDK2 DC50=62 nM and CDK9 DC50=33 nM . PROTAC CDK2/9 Degrader-1 suppresses prostate cancer PC-3 cell proliferation IC50=0.12 AAasAasAAmuM by effectively blocking the cell cycle in S and G2/M phases. PROTAC CDK2/9 Degrader-1 is a PROTAC by tethering CDK inhibitor with Cereblon ligand.





