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PROTAC cGAS degrader-1
GENERAL CATALOGUE

PROTAC cGAS degrader-1

HY-172208 · 1 mg

MedChemExpress · Cat: HY-172208

₹500 – ₹750 approx.This price excludes freight and taxes. Please RFQ to get the final price.

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Catalog No: HY-172208
Category: Immunology Inflammation
Pack Size: 1 mg
Brand: MedChemExpress

Description

PROTAC cGAS degrader-1 Compound TH35 is an effective and selective cGAS PROTAC degrader, with DC50 values of 0.9 ?M and 4.6 ?M in THP-1 and RAW 264.7 cells, respectively. PROTAC cGAS degrader-1 can inhibit the activation of cGAS signaling induced by dsDNA. PROTAC cGAS degrader-1 has anti-inflammatory activity and can be used in the research of cGAS-related inflammatory diseases. Pink: cGAS inhibitor HY-133916 ; Black: Linker HY-W411604 ; Blue: E3 ligase ligand HY-43722

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