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PROTAC CYP1B1 degrader-1
GENERAL CATALOGUE

PROTAC CYP1B1 degrader-1

HY-146393 · 1 mg

MedChemExpress · Cat: HY-146393

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Catalog No: HY-146393
CAS No: 2411389-67-6
Category: Metabolic Enzyme Protease
Pack Size: 1 mg
Brand: MedChemExpress

Description

PROTAC CYP1B1 degrader-1 Compound 6C , a ?-naphthoflavone chimera derivative, is able to eliminate cytochrome P450 CYP 1B1-mediated agent resistance via targeted CYP1B1 degradation, with IC50s of 95.1 and 9838.6 nM for CYP1B1 and CYP1A2, respectively. PROTAC CYP1B1 degrader-1 can be used for the research of CYP1B1-overexpressing prostate cancer.

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