GENERAL CATALOGUE
PROTAC EGFR degrader 11
HY-161633 · 1 mg
MedChemExpress · Cat: HY-161633
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Manufacturer product page
medchemexpress.com/protac-egfr-degrader-11.htmlCatalog No: HY-161633
CAS No: 3034244-71-5
Category: JAK STAT Signaling
Pack Size: 1 mg
Brand: MedChemExpress
Description
PROTAC EGFR degrader 11 Compound B71 is a PROTAC degrader for epidermal growth factor receptor EGFR , with DC50 100 nM. PROTAC EGFR degrader 11 binds CRBN-DDB1 with a Ki of 36 nM. PROTAC EGFR degrader 11 degrades EGFR, focal adhesion kinase FAK , and RSK1, inhibits the proliferation of BaF3 wild type and EGFR mutants, with IC50 <100 nM.
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