

HY-171958 · 50 mg
MedChemExpress · Cat: HY-171958
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medchemexpress.com/protac-egfr-degrader-12.htmlDescription
PROTAC EGFR degrader 12 example 1 is a PROTAC degrader targeting EGFR that can effectively degrade EGFR mutants, but has little effect on EGFR WT. PROTAC EGFR degrader 12 shows IC50s against EGFRL858R-T790M NCI-H1975 cells , EGFRL858R NCI-H3255 cells , and EGFRL858R-T790M-L797S NCI-H1975+CS cells of all <50 nM.







