GENERAL CATALOGUE
PROTAC EGFR degrader 13
HY-158313 · 50 mg
MedChemExpress · Cat: HY-158313
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Manufacturer product page
medchemexpress.com/protac-egfr-degrader-13.htmlCatalog No: HY-158313
CAS No: 2861227-35-0
Category: JAK STAT Signaling
Pack Size: 50 mg
Brand: MedChemExpress
Description
PROTAC EGFR degrader 13 compound 106 is an EGFR PROTAC degrader with a DC50 of 0.1 ?M. PROTAC EGFR degrader 13 has proliferation inhibitory activity on cell Ba/F3-TEL-EGFR-T790M-L858R-C797S with an IC50 of 15.6 nM. PROTAC EGFR degrader 13 can be used for the study of EGFR-related diseases such as cancer Pink: Target protein ligand; Blue: E3 ligand HY-14658 ; Black: linker HY-W262798 ; E3 ligand + linker: HY-W998306 .
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