PROTAC FLT-3 degrader 4

Name: PROTAC FLT-3 degrader 4
Brand: MedChemExpress

HY-158325 · 50 mg

MedChemExpress · Cat: HY-158325

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medchemexpress.com/protac-flt-3-degrader-4.html

Catalog No: HY-158325

CAS No: 2956722-48-6

Category: Apoptosis

Pack Size: 50 mg

Brand: MedChemExpress

Description

PROTAC FLT-3 degrader 4 is an orally active CRBN-based FLT3-PROTAC degrader that potently induces FLT3-ITD degradation through the ubiquitin-proteasome system. PROTAC FLT-3 degrader 4 shows highly selective to FLT3-ITD mutant acute myeloid leukemia AML cells. Blue: CRBN ligand, Black: linker; Pink: FLT3 inhibitor .