GENERAL CATALOGUE
PROTAC FLT-3 degrader 5
HY-175040 · 50 mg
MedChemExpress · Cat: HY-175040
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Manufacturer product page
medchemexpress.com/protac-flt3-gspt1-ikzf1-3-degrader-1.html...Catalog No: HY-175040
Category: Immunology Inflammation
Pack Size: 50 mg
Brand: MedChemExpress
Description
PROTAC FLT-3 degrader 5 is a FLT3 PROTAC degrader DC50 = 1.2 nM . PROTAC FLT-3 degrader 5 functions as a molecular glue to degrade cereblon substrates GSPT1 and IKZF1/3. PROTAC FLT-3 degrader 5 exhibits antiproliferative activity against drug-resistant acute myeloid leukemia AML cells and is potentially useful in AML research. Pink: FLT3/GSPT1/IKZF1/3 ligand: HY-169374 ; Blue: Thalidomide: HY-14658 ; Black: linker; Thalidomide + linker: HY-W1123823 .
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