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PROTAC GPX4 degrader-2
GENERAL CATALOGUE

PROTAC GPX4 degrader-2

HY-162106 · 50 mg

MedChemExpress · Cat: HY-162106

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Catalog No: HY-162106
Category: Apoptosis
Pack Size: 50 mg
Brand: MedChemExpress

Description

PROTAC GPX4 degrader-2 compound 18a is a proteolysis targeting chimeras PROTACs that can degrade glutathione peroxidase 4 GPX4 , with the DC50, 48h value of 1.68 ?M. PROTAC GPX4 degrader-2 induces the accumulation of lipid peroxides and mitochondrial depolarization, subsequently triggering ferroptosis. PROTAC GPX4 degrader-2 has anti-proliferative effect.

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