

HY-162106 · 50 mg
MedChemExpress · Cat: HY-162106
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medchemexpress.com/protac-gpx4-degrader-2.htmlDescription
PROTAC GPX4 degrader-2 compound 18a is a proteolysis targeting chimeras PROTACs that can degrade glutathione peroxidase 4 GPX4 , with the DC50, 48h value of 1.68 ?M. PROTAC GPX4 degrader-2 induces the accumulation of lipid peroxides and mitochondrial depolarization, subsequently triggering ferroptosis. PROTAC GPX4 degrader-2 has anti-proliferative effect.







