GENERAL CATALOGUE
PROTAC HDAC degrader-2
HY-174444 · 50 mg
MedChemExpress · Cat: HY-174444
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Manufacturer product page
medchemexpress.com/protac-hdac-degrader-2.htmlCatalog No: HY-174444
Category: Cell Cycle DNA Damage
Pack Size: 50 mg
Brand: MedChemExpress
Description
PROTAC HDAC degrader-2 is a selective IIb HDACs PROTAC degrader, with DC50s of 13 nM for HDAC6, 29 nM for HDAC10, respectively. PROTAC HDAC degrader-2 exhibits low cytotoxicity against hematological and solid cancer cell lines. PROTAC HDAC degrader-2 can be used for the chemical knockdown of class IIb HDACs. Pink: HDAC ligand : HY-174471 , Blue: E3 ligase CRBN Ligand HY-131717 , E3 ligase ligand-linker conjugate HY-174473 .
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