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PROTAC HDAC8 Degrader-2
GENERAL CATALOGUE

PROTAC HDAC8 Degrader-2

HY-168175 · 50 mg

MedChemExpress · Cat: HY-168175

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Catalog No: HY-168175
Category: Cell Cycle DNA Damage
Pack Size: 50 mg
Brand: MedChemExpress

Description

PROTAC HDAC8 Degrader-2 compound 32a is a degrader of HDAC8 with a DC50 of 8.9 nM and HDAC6 with a DC50 of 14.3 nM. PROTAC HDAC8 Degrader-2 is composed of PROTAC target protein ligand HDAC8 ligand 1 HY-168176 red part , E3 ligase ligand Thalidomide-4-OH HY-103596 blue part and PROTAC Linker 1,5-Diaminopentane HY-W540541 black part , among which the conjugate of E3 ubiquitin ligase ligand + Linker is Thalidomide-NH-C5-NH2 HY-134986 .

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