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PROTAC HIF-1? degrader-1
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PROTAC HIF-1? degrader-1

HY-168641 · 5 mg

MedChemExpress · Cat: HY-168641

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Catalog No: HY-168641
Category: Apoptosis
Pack Size: 5 mg
Brand: MedChemExpress

Description

PROTAC HIF-1? degrader-1 compound V2 is a potent hypoxia-inducible factor-1? HIF-1? PROTAC degrader with an IC50 value of 7.54 AAasAasAAmuM. PROTAC HIF-1? degrader-1 shows anti-proliferative activity. PROTAC HIF-1? degrader-1 decreases the HIF-1? protein expression. PROTAC HIF-1? degrader-1 induces apoptosis. Pink: ligand for target protein HY-111387 ; black: linker HY-W013731 ; Blue: E3 ligase ligand HY-112078 .

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