GENERAL CATALOGUE
PROTAC IRAK4 degrader-2
HY-135382 · 50 mg
MedChemExpress · Cat: HY-135382
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Manufacturer product page
medchemexpress.com/protac-irak4-degrader-2.htmlCatalog No: HY-135382
CAS No: 2374122-27-5
Category: Immunology Inflammation
Pack Size: 50 mg
Brand: MedChemExpress
Description
PROTAC IRAK4 degrader-2 Compound 9 is a PROTAC-based IRAK4 degrader that affords potent IRAK4 degradation with a DC50 in peripheral blood mononuclear cells PBMCs cells of 151 nM. PROTAC IRAK4 degrader-2 induce a reduction of IRAK4 protein levels with a DC50 of 36 nM in PBMC cells. PROTAC IRAK4 degrader-2 also leads to the inhibition of multiple cytokines in PBMCs.
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