

HY-159788 · 5 mg
MedChemExpress · Cat: HY-159788
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medchemexpress.com/protac-k-ras-degrader-4.htmlDescription
PROTAC K-Ras Degrader-4 Compound 4 is a PROTAC degrader for KRAS that degrades KRASG12D in GP5d and degrades KRASG12V in cell SW620 with DC50s of 1 nM and 13 nM. PROTAC K-Ras Degrader-4 inhibits MAPK signaling pathway. Pink: ligand for target protein pan-KRAS degrader 1 HY-162960 ; Black: linker HY-159790 ; Blue: ligand for E3 ligase VHL HY-W998248







