GENERAL CATALOGUE
PROTAC MAGL degrader-1
HY-173369 · 50 mg
MedChemExpress · Cat: HY-173369
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Manufacturer product page
medchemexpress.com/protac-magl-degrader-1.htmlCatalog No: HY-173369
Category: Metabolic Enzyme Protease
Pack Size: 50 mg
Brand: MedChemExpress
Description
PROTAC MAGL degrader-1 is an orally active PROTAC agent that simultaneously targets monoacylglycerol lipase MAGL and E3 ubiquitin ligase MDM2. PROTAC MAGL degrader-1 degrades MAGL and inhibits the binding of MDM2 to p53. PROTAC MAGL degrader-1 can partially penetrate the blood-brain barrier BBB . PROTAC MAGL degrader-1 induces glioblastoma stem cells GSCs apoptosis. E3 ligase ligand: HY-128837; target protein ligand + linker: HY-173370; target protein inhibitor: HY-15249 .
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