

HY-162930 · 5 mg
MedChemExpress · Cat: HY-162930
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medchemexpress.com/protac-mettl3-degrader-1.htmlDescription
PROTAC METTL3 degrader 1 Compound KH12 is a VHL-based PROTAC METTL3 degrader DC50: 220 nM in MOLM-13 cells . PROTAC METTL3 degrader 1 inhibits METTL3/14 complex with an IC50 value of 341 nM. PROTAC METTL3 degrader 1 has anti-proliferative activities against AML cells. Black: Linker HY-ER002 ; Red: METTL3 ligand HY-115717 ; Blue: VHL ligand HY-120217 .

