GENERAL CATALOGUE
PROTAC PARP1 degrader-1
HY-158045 · 5 mg
MedChemExpress · Cat: HY-158045
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medchemexpress.com/protac-parp1-degrader-1.htmlCatalog No: HY-158045
Category: Cell Cycle DNA Damage
Pack Size: 5 mg
Brand: MedChemExpress
Description
PROTAC PARP1 degrader-1 Compound CN0 is a PROTAC degrader of PARP1. PROTAC PARP1 degrader-1 activates the cGAS/STING immunity pathway and eventually enhances T cell killing of tumor cells. PROTAC PARP1 degrader-1 inhibits DNA damage repair, resulting in highly efficient accumulation of cytosolic DNA fragments Blue: CRBN ligand, Black: linker; Pink: PARP1 inhibitor .