GENERAL CATALOGUE
PROTAC PI3K/110? degrader-2
HY-174469 · 50 mg
MedChemExpress · Cat: HY-174469
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medchemexpress.com/protac-pi3k-110%CE%B2-degrader-2.html
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Catalog No: HY-174469
CAS No: 3070438-79-5
Category: Apoptosis
Pack Size: 50 mg
Brand: MedChemExpress
Description
PROTAC PI3K/110? degrader-2 is a selective PI3K/p110? PROTAC degrader. PROTAC PI3K/110? degrader-2 can significantly degrade 110? protein and inhibit the expression of P-glycoprotein. PROTAC PI3K/110? degrader-2 can increase the level of reactive oxygen species ROS . PROTAC PI3K/110? degrader-2 exerts anti-tumor effects by activating the endoplasmic reticulum stress ERS -mediated mitochondrial apoptosis pathway and inhibiting the AKT/Bcl-2 signaling pathway. PROTAC PI3K/110? degrader-2 can be used for research on cancer. Pink: PI3K/110? Ligand HY-75124 ; Blue: VHL Ligand HY-125845 ; Black: Linker HY-W002042 .
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