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PROTAC SARS-CoV-2 Mpro degrader-2
GENERAL CATALOGUE

PROTAC SARS-CoV-2 Mpro degrader-2

HY-157805 · 50 mg

MedChemExpress · Cat: HY-157805

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Catalog No: HY-157805
CAS No: 3057294-32-0
Category: Anti-infection
Pack Size: 50 mg
Brand: MedChemExpress

Description

PROTAC SARS-CoV-2 Mpro degrader-2 Compound 6 is a potent PROTAC degrader of SARS-CoV-2 Mpro. PROTAC SARS-CoV-2 Mpro degrader-2 has broad-spectrum antiviral activity against CoVs, including SARS-CoV-2 EC50 = 10.8 ?M , HCoV-OC43 EC50 = 1.6 ?M and HCoV-229E EC50 = 6.5 ?M . PROTAC SARS-CoV-2 Mpro degrader-2 exhibits potent activity against SARS-CoV-2 in Calu-3 cells, with an EC50 of 0.89 ?M.

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