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PROTAC SMARCA2/4-degrader-18
GENERAL CATALOGUE

PROTAC SMARCA2/4-degrader-18

HY-163871 · 50 mg

MedChemExpress · Cat: HY-163871

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Catalog No: HY-163871
CAS No: 2568276-91-3
Category: Epigenetics
Pack Size: 50 mg
Brand: MedChemExpress

Description

PROTAC SMARCA2/4-degrader-18 Compound I-348 is a PROTAC degrader for catalytic subunit of the SWI/SNF complex SMARCA2 and SMARCA4. PROTAC SMARCA2/4-degrader-18 degrades SMARCA2 in A549 with DC50 100 nM, degrades SMARCA4 in MV411 with DC50 100 nM. Pink: Ligand for Target Protein HY-159531 ; Black: Linker HY-76547 ; Blue: Ligand for E3 Ligase HY-125845

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