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PROTAC SMARCA2/4-degrader-5
GENERAL CATALOGUE

PROTAC SMARCA2/4-degrader-5

HY-159456 · 50 mg

MedChemExpress · Cat: HY-159456

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Catalog No: HY-159456
CAS No: 2568277-84-7
Category: Epigenetics
Pack Size: 50 mg
Brand: MedChemExpress

Description

PROTAC SMARCA2/4-degrader-5 Compound I-437 is a PROTAC degrader for catalytic subunit of the SWI/SNF complex SMARCA2 and SMARCA4. PROTAC SMARCA2/4-degrader-5 degrades SMARCA2 in MV411 and in A549 with DC50 100 nM, degrades SMARCA4 in MV411 with DC50 of 100-500 nM. Pink: Ligand for target protein HY-159545 ; Black: Linker HY-159557 ; Blue: Ligand for E3 ligase S,R,S -AHPC HY-125845

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