

HY-159449 · 50 mg
MedChemExpress · Cat: HY-159449
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medchemexpress.com/protac-smarca2-degrader-5.htmlDescription
PROTAC SMARCA2 degrader-5 Compound I-425 is a PROTAC degrader for catalytic subunit of the SWI/SNF complex SMARCA2. PROTAC SMARCA2 degrader-5 degrades SMARCA2 in MV411 and in A549 with DC50 100 nM, degrades SMARCA4 with DC50 of 100-500 nM. Pink: Ligand for target protein HY-159531 ; Black: Linker HY-159538 ; Blue: Ligand for E3 ligase S,R,S -AHPC HY-125845

