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PROTAC STING degrader-3
GENERAL CATALOGUE

PROTAC STING degrader-3

HY-173414 · 1 mg

MedChemExpress · Cat: HY-173414

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Catalog No: HY-173414
Category: Immunology Inflammation
Pack Size: 1 mg
Brand: MedChemExpress

Description

PROTAC STING degrader-3 Compound ST9 is a STING PROTAC degrader DC50: 0.62 ?M . PROTAC STING degrader-3 induces STING degradation via the ubiquitin-proteasome pathway. PROTAC STING degrader-3 exerts anti-inflammatory effects by inhibiting STING/TBK1/NF-?B signaling. PROTAC STING degrader-3 has renal protective effects and can be used in the study of acute kidney injury AKI Pink: STING ligand HY-47709 ; Blue: E3 ligase CRBN ligand HY-41547 ; Black: linker .

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