Proteinase 3 Mouse Monoclonal Antibody

Description

EnkiLife offers the Proteinase 3 Mouse Monoclonal Antibody. This antibody reacts with Human,Mouse species and is suitable for ICC,ELISA,FC application. Alternative Names of Immunogen: PRTN3; ACPA; CANCA. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: ICC 1:50-1:200,ELISA 1:5000-1:20000,FC 1:200-1:400 Background: Proteinase 3, also known as PRTN3. PRTN3 is a serine protease enzyme expressed mainly in neutrophil granulocytes. Its exact role in the function of the neutrophil is unknown but in human neutrophils proteinase 3 contributes to the proteolytic generation of antimicrobial peptides. It is also the epitope of anti-neutrophil cytoplasmic antibodies (ANCAs) of the cANCA (cytoplasmic subtype) class, a type of antibody frequently found in the disease Wegener's granulomatosis.